THE RED BLOOD CELLS CATALASE ACTIVITY IS INFLUENCED BY TARAXACUM OFFICINALE
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Як цитувати

Fulga, A., Pantea, V., Protopop, S., Tagadiuc, O., Todiras, M., & Gudumac, V. (2021). THE RED BLOOD CELLS CATALASE ACTIVITY IS INFLUENCED BY TARAXACUM OFFICINALE. InterConf, (58), 167-177. https://doi.org/10.51582/interconf.21-22.05.2021.020

Анотація

Natural antioxidants protect cells against oxidative stress, which is directly involved in ageing processes and in the pathogenesis of cardiovascular, neurodegenerative and neoplastic diseases. Taraxacum officinale (TO) due to its rich content of biologically active ingredients has been commonly used in traditional medicine. It contains a wide spectrum of compounds with antioxidant activity. The content depends of parts of this plant. The roots are rich in phenolic and terpene compounds, sesquiterpene lactones, fructosans and inulin, while leaves are rich in substances belonging to flavonoids, phenolic acids, coumarins and vitamins, especially vitamin A. The literature results prove that antioxidant activity of TO depends on several factors including the plant part, the solvent used, as well as the duration of extraction. The aim of this study was to evaluate and to compare the action of alcoholic extracts of roots and leaves of TO on RBC’s catalase activity. Material and methods. Raw Taraxacum officinale plant material consisted of dried leaves and roots were harvested from a natural site. The extracts for analysis were prepared using 20, 25, 40, 50 and 80% (v/v) ethanol mixtures used as solvents. The catalase activity was established by using RBC of healthy persons. Conclusions. Phytotherapeutic herbs and plants continue to play an important role in the discovery and development of drugs. Leaves and roots of dandelion represent a rich source of bioactive compounds for potential exploitation in nutraceuticals and pharmacological sectors. Taraxacum officinale has a high ability to act as an antioxidant. The highest influence on RBC’s catalase activity was reported in case of roots ethanolic extracts of 25%. These actions are realized due to multiple substances, whose content probably depends of ethanol’s concentration. Additional studies are needed to characterize biological activities of these extracts.

https://doi.org/10.51582/interconf.21-22.05.2021.020
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Посилання

Ryzhikov S l, Druzhinina IG, Riabicheva TG, Varaksin NA. [The standardization of technique of detection of blood cells cytokine production ex vivo]. Klin Lab Diagn. 2011 Nov; (11):49–53.

Gudumac V, Rîvneac V, Tagadiuc O, Sardari V, Rîvneac E, Andronache L, et al. Metode de cercetare a metabolismului hepatic. Elabor Metodică Sub Red Gudumac V USMF „Nicolae Testemiţanu” Chişinău. 2012;

Schütz K, Kammerer DR, Carle R, Schieber A. Characterization of phenolic acids and flavonoids in dandelion (Taraxacum officinale WEB. ex WIGG.) root and herb by high-performance liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 2005 Jan 30; 19(2):179–86.

Westerman L, Roddick JG. Annual Variation in Sterol Levels in Leaves of Taraxacum officinale Weber. Plant Physiol. 1981 Oct 1; 68(4):872–5.

Rodriguez-Ortega M. Actividad antiviral contra el virus de la fiebre amarilla, cepa vacunal17D, de extractos de hojas de Taraxacum officinale GH Weber ex Wiggers. Boletin Latinoam Caribe Plantas Med Aromat. 2013 Jul 1; 12:346–55.

Grauso L, Emrick S, de Falco B, Lanzotti V, Bonanomi G. Common dandelion: a review of its botanical, phytochemical and pharmacological profiles. Phytochem Rev. 2019 Aug 1; 18.

Mir M amin, Sawhney SS, Jassal MMS. Qualitative and quantitative analysis of phytochemicals of Taraxacum officinale. J Pharm Pharmocology. 2013 Jan 1; 2:001–5.

Popescu M, Dinu M, Ursache D. Contributions to the pharmacognostical and phytobiological study on Taraxacum officinale (L.) Weber. Farmacia. 2010 Sep 1; 58:646–53.

Hu C, Kitts DD. Antioxidant, Prooxidant, and Cytotoxic Activities of Solvent-Fractionated Dandelion (Taraxacum officinale) Flower Extracts in Vitro. J Agric Food Chem. 2003 Jan 1; 51(1):301–10.

Khan A, Arif K, Munir B, Kiran S, Jalal F, Qureshi N, et al. Estimating Total Phenolics in Taraxacum officinale (L.) Extracts. Pol J Environ Stud. 2018 Aug 6; 28.

Oseni L, Issah Y. Screening ethanolic and aqueous leaf extracts of Taraxacum officinalle for in vitro bacteria growth inhibition. J Pharm Biomed Sci. 2012 Jul 1; 20:1–4.

Sigstedt SC, Hooten CJ, Callewaert MC, Jenkins AR, Romero AE, Pullin MJ, et al. Evaluation of aqueous extracts of Taraxacum officinale on growth and invasion of breast and prostate cancer cells. Int J Oncol. 2008 May; 32(5):1085–90.

Esatbeyoglu T, Obermair B, Dorn T, Siems K, Rimbach G, Birringer M. Sesquiterpene Lactone Composition and Cellular Nrf2 Induction of Taraxacum officinale Leaves and Roots and Taraxinic Acid β-d-Glucopyranosyl Ester. J Med Food. 2017 Jan; 20(1):71–8.

Fulga A, Pantea V, Andronache L, Tagadiuc O, Todiras M, Gudumac V. Antioxidant activity of taraxacum officinale. InterConf. 2021 Mar 29; 264–80.

Fulga A, Pantea V, Andronache L, Tagadiuc O, Todiras M, Gudumac V. Erythrocytes glutathione peroxidase expression level is influenced by taraxacum officinale. InterConf [Internet]. 2021 Mar 28 [cited 2021 Apr 2]; Available from: https://ojs.ukrlogos.in.ua/ index.php/interconf/article/view/10322

Fulga A, Pantea V, Andronache L, Tagadiuc O, Gudumac V. The red blood cells glutathione reductase activity is influenced by taraxacum officinale. InterConf [Internet]. 2021 Mar 15 [cited 2021 Apr 2]; Available from: https://ojs.ukrlogos.in.ua/index.php/ interconf/article/view/9875

Jeyaseelan EC, Jenothiny S, Pathmanathan M, Jeyadevan J. Antibacterial activity of sequentially extracted organic solvent extracts of fruits, flowers and leaves of Lawsonia inermis L. from Jaffna. Asian Pac J Trop Biomed. 2012 Oct; 2(10):798–802.

Farahmandfar R, Kenari RE, Asnaashari M, Shahrampour D, Bakhshandeh T. Bioactive compounds, antioxidant and antimicrobial activities of Arum maculatum leaves extracts as affected by various solvents and extraction methods. Food Sci Nutr. 2019; 7(2):465–75.

Berkani F, Serralheiro ML, Dahmoune F, Ressaissi A, Kadri N, Remini H. Ultrasound Assisted Extraction of Phenolic Compounds from a Jujube By-Product with Valuable Bioactivities. Processes. 2020 Nov; 8(11):1441

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