Hemophilia is a disease caused by a mutation in the genes of factor VIII (8) and factor IX (9), proteins in the body that promote blood clotting. Over the past 50 years, success in the treatment of hemophilia has been achieved by modifying the therapy. Today it is important to develop new treatments, such as gene therapy. Improving this method can make life much easier for patients. The article gives a brief overview of this method and prospects for it’s use .
Doshi Bh., Arrud V. Gene therapy for hemophilia: what does the future hold? Therapeutic Advances in Hematology. 2018. Vol. 9 (9).
Gene Therapy for Hemophilia A: Where We Stand / Miaojin Zh. et al. Current Gene Therapy. 2020. Vol. 20 (2).
Gene therapy for hemophilia: Progress to date and challenges moving forward / Gollomp K. et. al. Transfusion and Apheresis Science. 2019. Vol. 58
Pickar A., Gersbach C. Gene therapies for hemophilia hit the mark in clinical trials. Nat Med. 2018. Vol. 24.
Ponder K. Gene therapy for hemophilia. Current Opinion in Hematology. 2006. Vol. 13.
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